Research & Trials

Full-scope cardiovascular research.

CRI is a full-scope cardiovascular research organization: a trial site for sponsors, a full-service CRO, and a developer of original diagnostics, all under one roof.

By the Numbers

12+

Studies Conducted

1,500+

Patients Enrolled

Active Sponsors

Therapeutic Areas

~2 wks

Avg. Site Activation

15+

Publications & Abstracts

Figures reflect combined site and investigator experience; study count is approximate pending final confirmation.

Track Record

Selected trials & validation work

Sponsor & Investigator Trials

Target BP I — Renal Denervation

2019–2022Published in Circulation

Prospective, international, sham-controlled, randomized, patient- and assessor-blinded trial of alcohol-mediated renal denervation for Ablative Solutions (2019–2022). Primary results published in Circulation.

ANTHOS TIMI-76

Active

Phase 3 trial evaluating abelacimab in high-risk patients with atrial fibrillation deemed unsuitable for current anticoagulants. Active.

Valencell

2023

Fingertip and wrist cuffless blood-pressure validation in older adults (2023); large-scale biometric studies across hypertensive and hypotensive populations.

EECP Research Programs

2022–2025

Enhanced external counterpulsation research spanning blood pressure, heart rate, and heart failure — including a 2025 NASA Human Research Program workshop selection on post-spaceflight reconditioning.

Thrive360

2022–2023

Virtual-reality cognitive behavioral therapy for stage 1–2 hypertension in outpatient cardiology (2022–2023).

Active studies

Active

Additional current sponsor work across cardiovascular therapeutics, devices, and AI, disclosed as each study becomes public.

Device, Diagnostic & AI Validation

Avive AED

Automated external defibrillator validation supporting FDA approval.

HealthSeers Technologies

Cairdio/Lightscope heart-murmur detection, Ainthoven AI ECG analysis, and Cloud Stream medical-imaging echo platforms.

Sudden Cardiac Death Screening

Student-athlete ECG screening with the Cody Stephens Foundation, supporting Texas House Bill 76 (the Cody Stephens Bill).

Sponsor Services

Six ways to work with CRI

Every engagement follows the same four-part structure: overview, what's included, deliverables, and an indicative timeline. Timelines are ranges, never fixed commitments.

Focus

Therapeutic areas & modalities

Cardiovascular Focus

Heart failureCoronary artery diseaseHypertensionAtrial fibrillation & arrhythmiaLipids & preventive cardiologyStructural heartPeripheral vascular diseaseCardiometabolic & diabetes

Therapeutics

Sponsor drug trials across all phases.

Devices

Clinical validation of cardiovascular devices.

Diagnostics

Accuracy and performance studies for diagnostic tools.

AI & Digital Health

Real-world validation of algorithms and remote monitoring.

Beyond cardiovascular, CRI can extend into gynecology and urology through Dr. Vaseem Ali, double board-certified in both.

Site & Infrastructure

A research suite inside a working cardiology practice

CRI operates inside a working cardiology practice, Houston Cardiology Consultants (HCC), directly connected to our Principal Investigator. The front of the facility is an active clinical cardiology office; the back is a dedicated, separate research suite. That integration gives us a built-in cardiovascular patient population and direct, physician-led referral into trials, while keeping clinical care and research operations physically distinct.